What Is PRF Facial Treatment?
Medically reviewed by Mary Leighton Kohlmann Smith, NP — May 2026
Simply Injectables | Denver, CO | Est. 2014
PRF facial treatment in Denver is a injectable aesthetic treatment that uses your body’s own growth factors to support collagen production, improve skin texture, and restore volume over time.
Platelet-Rich Fibrin (PRF) is created from a small sample of your blood. After it’s processed in a centrifuge, the final solution contains platelets, fibrin, white blood cells, and growth factors that help stimulate your body’s natural healing response.
At Simply Injectables, PRF is offered in two forms:
- PRF — a liquid version injected into targeted areas of the face, neck, and hands
- PRF Gel — a thicker, newer version of PRF this is processed to create a consistency closer to a filler, used to restore subtle volume in delicate areas like under the eyes
PRF is 100% natural — derived entirely from your own blood with no synthetic additives.
PRF Facial Treatment at a Glance
- Treatment type: regenerative injectable
- Common concerns: under-eye hollowness, skin texture, early volume loss, and visible signs of aging in the neck and hands
- Downtime: typically 3–5 days
- Timeline: gradual improvement over several weeks, continuing for months
- Recommended plan: 1–2 treatments spaced 4–6 weeks apart
- Approach: 100% natural — uses your own biological material
Why Patients in Denver Are Choosing PRF
A lot of people are looking for something that feels aligned with how their body already works.
PRF fits into that space. It supports your skin using your own biology — no synthetic materials — and the results build gradually over time. For many patients, that feels more natural — both in how it works and how it looks.
Research into PRF is ongoing, and results vary by individual. If you’re curious about the science behind it, you can learn more about the Natural Benefits of PRF and PRF Gel Treatments in Denver here.
At Simply Injectables, the focus is on results that feel like you — just more rested, more even, or a little more refreshed.
PRF and PRF Gel
PRF can be used in a couple of different ways, depending on what you’re trying to address.
PRF (liquid form) is injected into targeted areas like under the eyes, cheeks, neck, and hands to support tissue health and skin quality from within.
PRF Gel is a newer version processed to create a thicker consistency. It’s used in areas where a small amount of volume makes a meaningful difference — particularly under the eyes. Because it’s derived from your own blood, it works well in delicate areas where the skin is thinner and traditional filler may be too heavy.
The gel looks more consistent — almost like a filler — but is still 100% natural.
PRF and PRF Gel can also be combined with dermal filler for enhanced results.
PRF Compared to Other Options
| Feature | PRF / PRF Gel | PRP | Dermal Fillers |
| Source | Your own blood | Your own blood | Synthetic (hyaluronic acid) |
| Growth factor release | Gradual (fibrin matrix) | Faster release | Not applicable |
| Focus | Skin quality + subtle volume | Skin quality | Immediate volume |
| Natural | 100% natural | Natural | Synthetic |
| Timeline | Builds over time | Builds over time | Immediate change |
What PRF Can Help With
Skin Quality and Collagen Support
Collagen naturally declines over time, which is when changes in texture, elasticity, and brightness start to show.
PRF supports the skin by delivering growth factors that signal your body to rebuild and repair. Over time, this can lead to smoother texture and more even tone.
Under-Eye Hollowness
The under-eye area is often one of the first places people notice changes.
PRF Gel is used here to add a small amount of volume while also supporting the skin itself. The goal is a softer, more rested appearance.
Neck and Hand Rejuvenation
PRF and PRF Gel can also be injected into the neck and hands to support skin quality and tissue health in areas that show early signs of aging.
Am I a Good Candidate for PRF?
PRF may be a good fit for people who:
- want a more natural approach to skin rejuvenation
- are comfortable with gradual improvement over time
- are noticing early signs of volume loss or skin changes
want to address under-eye concerns without traditional filler - are interested in neck or hand rejuvenation
It’s not appropriate for everyone. Certain medical conditions may affect whether PRF is recommended, which will be reviewed during your consultation.
Who Performs PRF Treatments at Simply Injectables?
All treatments at Simply Injectables are performed by licensed medical professionals with specialized training in injectables and facial anatomy.
The practice has been established since 2014 and is led by experienced providers who focus specifically on aesthetic and regenerative treatments.
How PRF Fits Into a Treatment Plan
PRF can be done on its own or as part of a broader plan depending on your goals.
Some patients also include:
- Botox for expression lines
- Dermal fillers for added structure or volume
- PRF for Sexual Enhancement
You can review a full list of our services and pricing here.
Frequently Asked Questions About PRF Facial Treatment in Denver
Most people start with a series of 1–2 treatments spaced 4–6 weeks apart, followed by maintenance once or twice a year.
Appointments usually take about 60–90 minutes.
Some changes may be noticeable within a few weeks, with continued improvement over a few months.
There is some mild discomfort during the blood draw and injections. Numbing cream is used to help with comfort.
PRF is processed differently than PRP, allowing it to retain additional components — including a fibrin matrix — and release growth factors over a longer period of time. PRF Gel is the newest version, which creates a thicker, more filler-like consistency from the blood.
Mild redness, swelling, or bruising is common for a few days.
Yes, PRF can be combined with dermal filler for enhanced results, depending on your goals and treatment plan.
At Simply Injectables, we primarily use PRF in the under-eye area and cheeks, but it can also be used in the neck and hands.
What to Expect at Simply Injectables
The process starts with a consultation where your provider evaluates your skin and talks through your goals.
From there, a plan is created based on your timeline and what feels realistic for you.
Treatments are performed with a focus on balance, comfort, and natural-looking results.
Book Your PRF Consultation in Denver
If you’re considering PRF, the next step is a consultation to see if it fits your goals.
You can book your consultation for PRF in Denver online here.
Important Information
Simply Injectables is located in Denver, Colorado. PRF and PRF Gel treatments are performed by licensed medical professionals. Individual results vary. This content is for informational purposes only and does not replace medical advice.